Troglitazone‡Meglitinides Nateglinide, Repaglinide, MitiglinideDipeptidyl peptidase-4 (DPP-4) inhibitors Alogliptin,† Saxagliptin,† Sitagliptin, VildagliptinGlucagon-like peptide-1 analog ExenatideAmylin analog PramlintideInsulin analogs amaryl oral acting (Insulin glargine, Insulin detemir)Dual PPAR agonists Aleglitazar†, Muraglitazar§.

(November 2007)Please help improve this article by adding citations to reliable sources. Unverifiable material may be challenged amaryl oral removed.GlimepirideSystematic (IUPAC) name3-ethyl-N,N-bis (3-ethyl-4-methyl-2-oxo-5H-pyrrol-2-yl)- 4-methyl-2-oxo-5H-pyrrole-1- carboxamideIdentifiersCAS number 93479-97-1ATC code A10BB12PubChem 3476DrugBank APRD00381Chemical dataFormula C24H34N4O5SMol. mass 490.617 g/molPharmacokinetic dataBioavailability ?Protein binding >99.5%Metabolism amaryl oral ?Half life amaryl oral amaryl oral ?Therapeutic considerationsPregnancy cat. ?Legal amaryl oral ?Glimepiride is a medium-to-long acting sulfonylurea amaryl oral drug. It is marketed as Amaryl by Sanofi-Aventis. Glimepiride is the first third-generation sulfonylurea, and is very potent.Contents [hide]1 Indications2 Adverse effects3 Contraindications4 Interactions5 Pharmacology6 Mechanism of actionMain article: SulfonylureaGlimepiride distinctly lower the blood glucose level by both defects of NIDDM, by stimulating pancreatic beta.

considerationsPregnancy cat. ?Legal statusRoutes ?Glimepiride is a medium-to-long acting sulfonylurea.